AMD GPU system optimization

This guide outlines system setup and tuning suggestions for AMD hardware to optimize performance for specific types of workloads or use cases. The contents are structured according to the hardware:

AMD Instinct™

• AMD Instinct MI355X

• AMD Instinct MI350X

• AMD Instinct MI325X

• AMD Instinct MI300X

• AMD Instinct MI300A

• AMD Instinct MI250 / MI250X

• AMD Instinct MI210

• AMD Instinct MI100

AMD Radeon™ and Ryzen™

• AMD RDNA3.5 system optimization

• AMD RDNA2 system optimization

Common system settings

• GPU isolation techniques

• BAR access limits